Conditions > Mast cell activation

Mast Cell Activation Syndrome (MCAS)

When your immune system won’t stop overreacting, it’s more than just “being sensitive.” You deserve real answers — and lasting relief.

Overview

Mast Cell Activation Syndrome (MCAS) is often invisible to others — but overwhelming to live with. You may feel like you’re reacting to everything: foods, smells, temperature, stress. And when you’ve brought it up, you’ve likely been met with dismissal or confusion.

At GAIN, we take your symptoms seriously. We specialize in complex immune dysregulation like MCAS, and we’re here to help you connect the dots, calm your system, and reclaim your quality of life.

What is Mast Cell Activation Syndrome (MCAS)?

MCAS is a condition where mast cells — part of your immune system — become overly reactive and release chemicals (like histamine) inappropriately. This leads to widespread symptoms across multiple body systems, even without a traditional allergy trigger.

MCAS can be unpredictable, exhausting, and deeply misunderstood — especially by providers unfamiliar with it.

Common Symptoms of MCAS

Flushing, itching, or skin rashes

Brain fog, dizziness, or anxiety

GI issues like nausea, cramping, or diarrhea

Heart palpitations or blood pressure swings

Reactions to heat, cold, exercise, or stress

Chemical, food, or fragrance sensitivitie

You don’t have to check every box to be taken seriously. We listen to your full experience.

How GAIN Can Help

At GAIN, we recognize MCAS as a real and often life-disrupting condition. Dr. Jones has deep expertise in mast cell disorders and takes the time to investigate your history, patterns, and triggers — not just your labs.

Our approach may include:

Therapeutic trials of mast cell stabilizers or antihistamines

Nutrition guidance for low-histamine diets

Identifying and managing co-occurring conditions (like POTS or EDS)

Gradual desensitization strategies when appropriate

We’ll build a plan that meets your nervous system and immune system where they are — and helps you move forward safely.

Why Patients Choose GAIN

Appointments are unrushed and validating

No referral required

We offer both in-person and telehealth visits

You’ll get a clear care plan — not just a handout

We understand that MCAS often overlaps with other immune issues

You’re not overreacting. Your body is — and we can help.

Book a consultation today and take the first step toward getting your system back under control — with real answers and a care plan that makes sense.

You deserve to be heard
You deserve to be heard
You deserve to be heard
You deserve to be heard
You deserve to be heard
You deserve to be heard
You deserve to be heard
You deserve to be heard
You deserve to be heard
You deserve to be heard
You deserve to be heard
You deserve to be heard
You deserve to be heard
You deserve to be heard
You deserve to be heard
You deserve to be heard

Your Healing Journey Starts Here

Book your consultation with Dr. Doug Jones and discover the relief you deserve today.